Treating a Gout Attack

  • Take an anti-inflammatory medication as soon as possible
  • Ice and elevate the joint
  • Drink plenty of fluids (no alcohol or sweet sodas)
  • Call your doctor and make an appointment
  • Relax; stress can aggravate gout
  • Ask family and friends to help you with daily tasks

Reducing Uric Acid Levels

 Medications that lower uric acid are intended to prevent gout attacks and keep the condition from becoming chronic. Your doctor will wait until your most recent gout attack is over before starting these medications, because taking them during an attack can worsen or prolong it. Taking these medications can be challenging  - as uric acid levels drop, crystals in your joints may shift , triggering more attacks. However, sticking with your treatment plan is the best way to prevent future attacks. Your doctor may prescribe an anti-inflammatory medication such as a low, but regular dose of colchicine or an NSAID, along with one of the medications below for the first six weeks to 12 months to prevent attacks. 


  • Allopurinol - Reduces the production of uric acid. 
  • Febuxostat - This medication may be an option if you develop side effects from allopurinol or have kidney disease. Like, allopurinol, this medication decreases the amount of uric acid made in the body.
  • Probenecid - This medication acts on the kidneys to help the body eliminate uric acid.
  • Lesinurad - This oral drug helps the body eliminate uric acid. It is used with a xanthine oxidase inhibitor (XOI), such as allopurinol or febuxostat, to enhance the effects for people whose gout is not controlled by optimally-dosed XOIs alone.
  • Krystexxa - This is used when standard medications are unable to lower the uric acid level, a condition known as refractory chronic gout. Pegloticase reduces uric acid quickly and to lower levels than other medications. 


The Gout Clinic is a Krystexxa Infusion Center. Krystexxa is an infusable medication that lowers uric acid to a level that can help dissolve and remove gout crystals—in months, not years. Krystexxa  works differently than other treatments you may have tried. It changes uric acid into a substance your body can get rid of easily to help relieve your gout symptoms. If you’ve tried other gout medicines and still have high uric acid and ongoing gout symptoms, KRYSTEXXA may be right for you.